Which substance is most commonly linked to recent fentanyl-related overdoses?

The substance most commonly linked to recent fentanyl-related overdoses is illegally produced fentanyl. This synthetic opioid is often manufactured in unregulated environments and frequently mixed with other substances, such as heroin or cocaine, to enhance potency. Users may be unaware of the presence of fentanyl, leading to a high risk of overdose due to the drug's strength. Illegally produced fentanyl can be significantly more potent than pharmaceutical-grade fentanyl, which contributes to the alarming increase in overdose fatalities.

Legally prescribed fentanyl, fentanyl patches, and lozenges are typically administered under medical supervision. While overdoses can occur with these forms, the current crisis is rooted in the proliferation of illicitly manufactured fentanyl that lacks quality control and oversight, resulting in a dangerous and unpredictable drug supply.