Where does most absorption of an ingested poison take place?

The small intestine is the primary site for the absorption of most ingested substances, including poisons. This is due to several factors: the small intestine has a larger surface area compared to the stomach and large intestine, allowing for more efficient absorption. It is lined with villi and microvilli, which significantly increase absorptive capacity by providing more area for the nutrients and toxins to interact with the intestinal wall.

Additionally, the small intestine has specialized sections, such as the duodenum, jejunum, and ileum, that not only facilitate absorption but also engage in the enzymatic breakdown of substances, making it easier for the body to absorb various compounds, including poisons. In the context of poisoning, the quicker absorption in the small intestine can lead to a faster onset of symptoms and potential toxicity, making it a critical consideration in emergency medical response.

The other options, while parts of the digestive system, do not play the same role in absorption. The stomach primarily serves for digestion and initial breakdown of substances, while the large intestine is more involved in water absorption and waste processing. The esophagus mainly functions as a conduit for food and does not absorb nutrients. Thus, the small intestine stands out as the most significant site for absorption of