What is the main deficiency when glucose levels continue to rise in the body?

When glucose levels continue to rise in the body, the primary issue is a lack of insulin to facilitate the transport of glucose into the cells. Insulin is a hormone produced by the pancreas that plays a crucial role in regulating blood sugar levels. It allows glucose to enter cells, where it can be used for energy or stored for future use.

Without sufficient insulin, glucose remains in the bloodstream instead of being taken up by the cells, leading to elevated blood sugar levels. This situation often occurs in conditions like diabetes, particularly type 1 diabetes, where there is little to no insulin production.

In this context, the correct answer reflects the underlying metabolic problem that causes hyperglycemia, or high blood sugar. Understanding this mechanism is essential for effectively managing conditions related to abnormal glucose metabolism.