Signs and symptoms of an anaphylactoid reaction are:

An anaphylactoid reaction and an anaphylactic reaction share many similarities in their signs and symptoms. Both reactions are mediated by the body’s immune response, leading to a spectrum of symptoms that may include hives, swelling, difficulty breathing, hypotension, and gastrointestinal issues. These reactions can occur rapidly and can be life-threatening, necessitating immediate medical attention.

Choosing the option indicating that the signs and symptoms are the same emphasizes the importance of recognizing that both reactions can present identically in terms of clinical manifestations, even though their underlying mechanisms may differ. Anaphylactic reactions are IgE-mediated, while anaphylactoid reactions do not involve IgE but still trigger similar symptoms through direct mast cell degranulation or other pathways. Understanding this helps EMTs and responders recognize and treat such reactions effectively, regardless of their underlying cause.