Myxedema coma is a complication of:

Myxedema coma is a severe and life-threatening complication of hypothyroidism, which is a condition where the thyroid gland does not produce enough thyroid hormones. In individuals with untreated or poorly managed hypothyroidism, factors such as infection, trauma, or exposure to cold can precipitate a myxedema coma. This condition is characterized by a drastic reduction in metabolic processes leading to signs such as severe lethargy, alterations in mental status, hypothermia, bradycardia, and in many cases, respiratory failure.

Thyroid hormones are crucial for maintaining metabolic functions in the body, including thermoregulation and heart function. When there is a critical deficiency, the body cannot maintain homeostasis, leading to the clinical manifestations seen in myxedema coma. Prompt recognition and treatment of this condition with thyroid hormone replacement and supportive care are essential to improving outcomes.

Other medical conditions listed, such as hypoadrenalism, late cold injury, and hypothermia, while they may present with overlapping symptoms or complications, do not specifically cause myxedema coma. Hypoadrenalism relates to issues with adrenal gland function, while late cold injury refers to frostbite or similar issues arising after prolonged exposure to cold. Hypothermia, although it can