An anaphylactoid reaction is also known as what?

An anaphylactoid reaction is characterized as a non-IgE-mediated reaction. This type of reaction mimics anaphylaxis but does not involve Immunoglobulin E antibodies, which are typically responsible for allergic responses. Instead, anaphylactoid reactions are caused by other mechanisms, such as direct release of mediators from mast cells and basophils, which can occur with certain medications, radiographic contrast agents, or other stimuli.

Understanding the distinction between anaphylactoid and anaphylactic reactions is crucial, as it influences treatment approaches and the understanding of the underlying mechanisms. While anaphylaxis is a result of sensitization and subsequent exposure to a specific allergen that triggers an IgE-mediated response, anaphylactoid reactions can occur without prior sensitization and do not rely on the immune system's IgE antibodies to cause the symptoms typically associated with severe allergic reactions.